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Phase 3 clinical trials are under way (see ClinicalTrials.gov for current registered studies), and whilst early Phase 2 results are encouraging, retatrutide is not legally available as a prescribed medicine in the UK outside of approved clinical trial settings

Lack of historical evidence to support folic acid exacerbation of the neuropathy caused by vitamin B12 deficiency

Many patients notice changes within days to a few weeks, depending on how deficient they were and how consistent the protocol is

See Figure 18.38 [13] for an illustration of the Z-track method